Glycine tert-butyl ester hydrochloride → HCID 66713533, compound

HRID 908834Notes

Reaction equation

HRID 908834 reaction equation
Cl.[C:2]([O:6][C:7](=[O:10])[CH2:8][NH2:9])([CH3:5])([CH3:4])[CH3:3].[CH2:11]([O:13][C:14]1[C:23]2[C:18](=[CH:19][C:20]([O:24][C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)=[CH:21][CH:22]=2)[C:17]([CH3:31])=[N:16][C:15]=1[C:32](O)=[O:33])[CH3:12]>>[C:2]([O:6][C:7](=[O:10])[CH2:8][NH:9][C:32]([C:15]1[N:16]=[C:17]([CH3:31])[C:18]2[C:23]([C:14]=1[O:13][CH2:11][CH3:12])=[CH:22][CH:21]=[C:20]([O:24][C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1)[CH:19]=2)=[O:33])([CH3:5])([CH3:4])[CH3:3]

Participants

3

Reactant 2

HCID 2725036Glycine tert-butyl ester hydrochlorideHCID 66712945HCID 66712945, compound

Product 1

HCID 66713533HCID 66713533, compound

Procedure

Synthesized from glycine tert-butyl ester hydrochloride and 4-ethoxy-1-methyl-7-phenoxy-isoquinoline-3-carboxylic acid in analogy to Example D-78 c); MS-(+)-ion: M+1=437.1.

Sources & evidence

ORD record
ord-7ed1fafdf1f84298ba1ceb10e728f607
Source dataset
uspto-grants-2011_09
Patent number
US08017625B2

Reaction notes

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