HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → HCID 11978507, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Oxalate | HCID 71081 | — |
| Reactant | 1-(3-chloropropyl)pyrrolidine Hydrochloride | HCID 11571916 | — |
| Reactant | HCID 67414458 | HCID 67414458 | — |
| Product | HCID 11978507 | HCID 11978507 | 4.1% |
Reaction Steps
Following the procedure described in example 2, but starting from 3-(4-fluoro-3-methoxyphenyl)prop-2-en-1-ol (600 mg), potassium hydroxide (456 mg, 85% wt) and 1-(3-chloropropyl)pyrrolidine, hydrochloride (618 mg) in dimethylsufoxide (5 mL) affords 40 mg of trans-1-{3-[3-(4-fluoro-3-methoxyphenyl)allyloxy]-propyl}pyrrolidine, oxalate as a solid melting at 143-144° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08017646B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-b381d164274b45aa87b56c1d31a04af0 |
| Source note | uspto-grants-2011_09 |