HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl Sulfoxide → Piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl Sulfoxide | HCID 679 | — |
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | HCID 23150783 | HCID 23150783 | — |
| Product | Piperidine | HCID 8082 | — |
| Product | Oxalate | HCID 71081 | — |
Reaction Steps
A Following the procedure described in example 7§B, but starting from trans-2,3-dihydro-6-[3-(3-iodopropoxy)prop-1-en-1-yl]benzo[1,4]dioxine (200 mg), piperidine (165 μL) and sodium carbonate (294 mg) in dimethylsulfoxide (1.8 mL) affords 172 mg of 1-{3-[3-(2,3-dihydrobenzo[1,4]dioxin-6-yl)allyl]oxy}propyl)piperidine, oxalate melting at 120° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08017646B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-9b7db83ec7644dc19202b209e8c91379 |
| Source note | uspto-grants-2011_09 |