Chlorotrimethylsilane → 2-(4-Dimethylamino-4-phenylcyclohexylidene)-N-phenylethyl-acetamide hydrochloride

Participants

Reaction Steps

2-(4-Dimethylamino-4-phenylcyclohexylidene)-N-phenylethylacetamide (225 mg, 0.62 mmol) was dissolved in ethyl methyl ketone (12 ml) with gentle heating and chlorotrimethylsilane (0.118 ml, 0.93 mmol) was added. After 2 h the product was isolated as a colourless solid in a yield of 86% (213 mg).

Provenance & Evidence