反应详情

2-(4-Dimethylamino-4-phenylcyclohexylidene)-N-[5-(1H-indol-3-yl)pentyl]acetamide (81 mg, 0.182 mmol) was dissolved in ethyl methyl ketone (3 ml), and chlorotrimethylsilane (0.035 ml, 0.27 mmol) was added. After 1.5 h the hydrochloride was isolated as a colourless solid with an m.p. of 174-183° C. in a yield of 71% (62 mg).