Diethyl Ether → HCID 11547748, compound

Participants

Reaction Steps

2-(4-Dimethylamino-4-phenylcyclohexylidene)-N-[6-(1H-indol-3-yl)hexyl]acetamide (78 mg, 0.17 mmol) was dissolved in ethyl methyl ketone (5 ml), and chlorotrimethylsilane (0.033 mol, 0.26 mmol) was added. After 1 h ether (10 ml) was added, and after 10 min the hydrochloride was isolated as a colourless solid with an m.p. of 160-164° C. in a yield of 87% (73 mg).

Provenance & Evidence