Chlorotrimethylsilane → HCID 11604570, compound

Participants

Reaction Steps

2-(4-Dimethylamino-4-pyridin-2-ylcyclohexylidene)-N-[2-(1H-indol-3-yl)ethyl]acetamide (210 mg, 0.52 mmol) was dissolved in ethyl methyl ketone (5 ml), and chlorotrimethylsilane (0.19 ml, 1.5 mmol) was added. After 1.5 h the hydrochloride was isolated as a beige-coloured solid with an m.p. of 147-150° C. in a yield of 89% (203 mg).

Provenance & Evidence