Chlorotrimethylsilane → HCID 11647293, compound

Participants

Reaction Steps

2-(4-Dimethylamino-4-pyridin-2-ylcyclohexylidene)-N-(3-phenylpropyl)acetamide (203 mg, 0.537 mmol was dissolved in ethyl methyl ketone (5 ml), and chlorotrimethylsilane (0.2 ml, 1.6 mmol) was added. After 1.5 h the hydrochloride was isolated as a colourless solid with an m.p. of 173-176° C. in a yield of 86% (190 mg).

Provenance & Evidence