反应详情

2-(4-Dimethylamino-4-phenylcyclohexyl)-N-[3-(1H-indol-3-yl)propyl]-acetamide (68 mg, 0.162 mmol) was dissolved in ethyl methyl ketone (5 ml), and chlorotrimethylsilane (0.033 ml, 0.245 mmol) was added. After 3 h it was possible to isolate the product as a colourless solid in a yield of 65% (54 mg) with an m.p. of 162-170° C.