Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → (2E)-3-(4-(methoxycarbonyl)phenyl)prop-2-enoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 1,4-Dioxane | HCID 31275 | — |
| 반응물 | methyl (E)-4-(3-(tert-butoxy)-3-oxoprop-1-en-1-yl)benzoate | HCID 42640359 | — |
| 생성물 | (2E)-3-(4-(methoxycarbonyl)phenyl)prop-2-enoic acid | HCID 1472795 | 64.5% |
반응 단계
The crude 4-((E)-2-tert-butoxycarbonyl-vinyl)-benzoic acid methyl ester (1.00 g, 3.81 mmol) was then treated with 4N HCl in dioxane (Aldrich, 4 mL, 16.0 mmol) at rt for 2 hrs to give 4-((E)-2-carboxyvinyl)-benzoic acid methyl ester (0.43 g, 64.5%, 2 steps) after work up.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08017607B2 |
| 출처 데이터셋 | uspto-grants-2011_09 |
| ORD ID | ord-d0b0e3e617164e5dbf99451ce4615227 |
| 출처 메모 | uspto-grants-2011_09 |