反应详情

The general methods described in Parts A and B of Example 2 were followed using 7-bromo-2-(ethoxymethyl)-1-(2-methylpropyl)-1H-imidazo[4,5-c][1,5]naphthyridine in lieu of 7-bromo-2-(ethoxymethyl)-1-(3-isopropoxypropyl)-1H-imidazo[4,5-c]quinoline and 2-oxazolidinone in lieu of 2-pyrrolidinone. The product, 3-[4-amino-2-ethoxymethyl-1-(2-methylpropyl)-1H-imidazo[4,5-c][1,5]naphthyridin-7-yl]-1,3-oxazolidin-2-one (0.125 g) was isolated as an white solid with yellow tinge, m.p. 174-176.5° C.