HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium Carbonate → HCID 86761409, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium Carbonate | HCID 11125 | — |
| Reactant | 4-Nitrobenzyl bromide | HCID 66011 | — |
| Reactant | 5-Bromo-3,4-dihydroxybenzaldehyde | HCID 85405 | — |
| Catalyst | Tetrabutylammonium Iodide | HCID 67553 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 86761409 | HCID 86761409 | — |
Reaction Steps
A mixture of 3-bromo-4,5-dihydroxy-benzaldehyde (2 g), 4-nitrobenzylbromide (2 g), lithium carbonate (680 mg) and a small amount of tetrabutylammonium iodide (ca 50 mg) in DMF (15 ml) was stirred at 60° C. for 4 h. The mixture was diluted with EtOAc and washed with water. The organic layer was dried (MgSO4), filtered and concentrated in vacuo. Yield: 2.82 g. MS-ESI: [M+H]+=352.0/354.0
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08017782B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-a601bca44115434e8403382ae38397ef |
| Source note | uspto-grants-2011_09 |