참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 5-Propylcyclohexane-1,3-dione | HCID 2737224 | — |
| 반응물 | 3-Aminocrotonitrile | HCID 5324720 | — |
| 반응물 | HCID 87388798 | HCID 87388798 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | HCID 67410453 | HCID 67410453 | — |
반응 단계
A mixture of the product of step c (59 mg), 3-aminocrotonitrile (12.3 mg) and 5-propylcyclohexane-1,3-dione (23.1 mg) in ethanol (5 ml) was stirred at 80° C. for 17 h. The reaction mixture was concentrated in vacuo and the residue was purified by preparative HPLC (Method B). Yield: 57 mg. MS-ESI: [M+H]+=591.3/593.3; HPLC: Rt=18.43 min. Diast. ratio: 9:1
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08017782B2 |
|---|
| 출처 데이터셋 | uspto-grants-2011_09 |
|---|
| ORD ID | ord-1838a73898564ef3830e76f7c0e3774a |
|---|
| 출처 메모 | uspto-grants-2011_09 |
|---|
