Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzylamine → (3S,4S,6R)-6-benzhydryl-4-benzylamino-tetrahydropyran-3-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzylamine | HCID 7504 | — |
| 반응물 | (1S,4R,6R)-4-benzhydryl-3,7-dioxa-bicyclo[4.1.0]-heptane | HCID 86605348 | — |
| 생성물 | (3S,4S,6R)-6-benzhydryl-4-benzylamino-tetrahydropyran-3-ol | HCID 66632020 | — |
반응 단계
(1S,4R,6R)-4-benzhydryl-3,7-dioxa-bicyclo[4.1.0]heptane 28d (0.019 g, 0.071 mmol) was reacted with benzylamine (0.15 g, 1.43 mmol) (Procedure E) to yield (3S,4S,6R)-6-benzhydryl-4-benzylamino-tetrahydropyran-3-ol, (+)-29h, 0.023 (85%, [α]D=(+)70.1, c=1, MeOH).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08017791B2 |
| 출처 데이터셋 | uspto-grants-2011_09 |
| ORD ID | ord-349b8217ac274e0fb907b522ce48d6f4 |
| 출처 메모 | uspto-grants-2011_09 |