HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzylamine → (3S,4R,6S)-6-benzhydryl-4-benzylamino-tetrahydropyran-3-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzylamine | HCID 7504 | — |
| Reactant | HCID 86605349 | HCID 86605349 | — |
| Product | (3S,4R,6S)-6-benzhydryl-4-benzylamino-tetrahydropyran-3-ol | HCID 11257315 | 86% |
Reaction Steps
(1R,4S,6S)-4-benzhydryl-3,7-dioxa-bicyclo[4.1.0]heptane 28b (0.03 g, 0.09 mmol) reacted with benzylamine (0.20 g, 1.88 mmol) (Procedure E) to yield (3S,4R,6S)-6-benzhydryl-4-benzylamino-tetrahydropyran-3-ol, (−)-29h, 0.03 g (Yield; 86%), [α]D=(−)70.6, c=1, MeOH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08017791B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-242ec9222113418f85dd1b9d742cd0a8 |
| Source note | uspto-grants-2011_09 |