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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 909810Generated: October 31, 2026

Hydrochloric Acid → 2-(4-Ethylbenzyl)phenol

https://huagongshe.com/reaction/909810

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactantα-(4-Ethylphenyl)-2-(phenylmethoxy)benzenemethanolHCID 67069123—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
Product2-(4-Ethylbenzyl)phenolHCID 11658557108.5%

Reaction Steps

Then a mixture of (2-benzyloxyphenyl)(4-ethylphenyl)methanol (78.5 g), 10% palladium activated carbon (5.2 g), concentrated hydrochloric acid (10.4 mL) and methanol (850 mL) was stirred under hydrogen atmosphere at room temperature for 24 hours. After filtering off the insolubles, the filtrate was evaporated under reduced pressure and then, the residue was distilled under reduced pressure to obtain the title compound (56.8 g) as a colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08017792B2
Source datasetuspto-grants-2011_09
ORD IDord-40716aebeb5344dda2449656d5a06df7
Source noteuspto-grants-2011_09