Piperidin-2-ylmethanol → HCID 67391717, compound

HRID 909827Notes

Reaction equation

HRID 909827 reaction equation
[OH:1][CH2:2][CH:3]1[CH2:8][CH2:7][CH2:6][CH2:5][NH:4]1.[Cl:9][C:10]1[CH:11]=[C:12]([B:17]([CH:19]([O:26][CH:27]([B:34]([C:36]2[CH:41]=[CH:40][C:39]([CH3:42])=[C:38]([Cl:43])[CH:37]=2)[OH:35])[C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)O)[CH:13]=[CH:14][C:15]=1[CH3:16]>C(O)C>[Cl:9][C:10]1[CH:11]=[C:12]([B:17]([CH:19]([O:26][CH:27]([B:34]([C:36]2[CH:41]=[CH:40][C:39]([CH3:42])=[C:38]([Cl:43])[CH:37]=2)[O:35][CH2:2][CH:3]2[CH2:8][CH2:7][CH2:6][CH2:5][NH:4]2)[C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[C:20]2[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=2)[O:1][CH2:2][CH:3]2[CH2:8][CH2:7][CH2:6][CH2:5][NH:4]2)[CH:13]=[CH:14][C:15]=1[CH3:16]

Participants

4

Reactant 2

HCID 94263Piperidin-2-ylmethanolHCID 67392188HCID 67392188, compound

Product 1

HCID 67391717HCID 67391717, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

The entitled compound (88 mg) was obtained by allowing 52 mg of 2-hydroxymethylpiperidine to act on 99 mg of bis(4,4′-(3-chloro-4-methylphenyl-hydroxyboryl)benzyl) ether in 1 mL of ethanol.

Sources & evidence

ORD record
ord-b851b218c5014d8d8a46513e089acb75
Source dataset
uspto-grants-2011_09
Patent number
US08017809B2

Reaction notes

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