HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trimethylsilyldiazomethane → HCID 57419860, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trimethylsilyldiazomethane | HCID 167693 | — |
| Reactant | 3-Bromo-4-fluorophenylacetic Acid | HCID 3416339 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 57419860 | HCID 57419860 | — |
Reaction Steps
A solution of (diazomethyl)trimethylsilane (12.87 mL) in diethyl ether was added to an ice-batch cooled solution of 2-(3-bromo-4-fluorophenyl)acetic acid (3 g) in dichloromethane (20 mL) and methanol (5 mL). The mixture was stirred for 10 min. and concentrated in vacuo to give methyl 2-(3-bromo-4-fluorophenyl)acetate (3.20 g) that was
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08017602B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-80960c89fff84353833007ac484a4262 |
| Source note | uspto-grants-2011_09 |