Benzamide → [4-Bromo-2-(2-phenyloxazol-4-yl)phenoxy]acetic acid

HRID 910035Notes

Reaction equation

HRID 910035 reaction equation
C([O:3][C:4](=[O:18])[CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([Br:13])=[CH:9][C:8]=1[C:14](=O)[CH2:15]Br)C.[C:19]([NH2:27])(=[O:26])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[Br:13][C:10]1[CH:11]=[CH:12][C:7]([O:6][CH2:5][C:4]([OH:3])=[O:18])=[C:8]([C:14]2[N:27]=[C:19]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[O:26][CH:15]=2)[CH:9]=1

Participants

3

Reactant 2

HCID 2331BenzamideHCID 57658801[4-Bromo-2-(2-bromoacetyl)phenoxy]acetic acid ethyl ester

Product 1

HCID 57658803[4-Bromo-2-(2-phenyloxazol-4-yl)phenoxy]acetic acid

Procedure

Title compound was prepared from [4-bromo-2-(2-bromoacetyl)phenoxy]acetic acid ethyl ester and benzamide according to GP5 and GP3: LC/MS (an10p8) Rt 2.6 min, m/z 374/376 [M+H]+.

Sources & evidence

ORD record
ord-0c1f5c9ae55c44ff9794c342fe2a03f0
Source dataset
uspto-grants-2011_09
Patent number
US08022063B2

Reaction notes

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