4-Methoxybenzamide → {4-Bromo-2-[2-(4-methoxyphenyl)oxazol-4-yl]phenoxy}acetic acid

HRID 910036Notes

Reaction equation

HRID 910036 reaction equation
C([O:3][C:4](=[O:18])[CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([Br:13])=[CH:9][C:8]=1[C:14](=O)[CH2:15]Br)C.[CH3:19][O:20][C:21]1[CH:29]=[CH:28][C:24]([C:25]([NH2:27])=[O:26])=[CH:23][CH:22]=1>>[Br:13][C:10]1[CH:11]=[CH:12][C:7]([O:6][CH2:5][C:4]([OH:3])=[O:18])=[C:8]([C:14]2[N:27]=[C:25]([C:24]3[CH:28]=[CH:29][C:21]([O:20][CH3:19])=[CH:22][CH:23]=3)[O:26][CH:15]=2)[CH:9]=1

Participants

3

Reactant 2

HCID 769594-MethoxybenzamideHCID 57658801[4-Bromo-2-(2-bromoacetyl)phenoxy]acetic acid ethyl ester

Product 1

HCID 57658821{4-Bromo-2-[2-(4-methoxyphenyl)oxazol-4-yl]phenoxy}acetic acid

Procedure

Title compound was prepared from [4-bromo-2-(2-bromoacetyl)phenoxy]acetic acid ethyl ester and 4-methoxybenzamide according to GP5 and GP3: LC/MS (an10p8) Rt 2.61 min, m/z 404 [M+H]+.

Sources & evidence

ORD record
ord-05be74e48112448e8e20bb4074e61555
Source dataset
uspto-grants-2011_09
Patent number
US08022063B2

Reaction notes

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