Benzeneacetamide → HCID 57658817, compound

HRID 910039Notes

Reaction equation

C([O:3][C:4](=[O:18])[CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([Br:13])=[CH:9][C:8]=1[C:14](=O)[CH2:15]Br)C.[C:19]1([CH2:25][C:26]([NH2:28])=[O:27])[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>>[CH2:25]([C:26]1[O:27][CH:15]=[C:14]([C:8]2[CH:9]=[C:10]([Br:13])[CH:11]=[CH:12][C:7]=2[O:6][CH2:5][C:4]([OH:3])=[O:18])[N:28]=1)[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

Participants

Reactant 2

HCID 7680Benzeneacetamide

HCID 57658801[4-Bromo-2-(2-bromoacetyl)phenoxy]acetic acid ethyl ester

Product 1

HCID 57658817HCID 57658817, compound

Procedure

Title compound was prepared from [4-bromo-2-(2-bromoacetyl)phenoxy]acetic acid ethyl ester and 2-phenylacetamide according to GP5 and GP3: LC/MS (an10p8) Rt 2.47 min, m/z 388 [M+H]+; 1H NMR (CDCl3): δ 4.22 (s, 2H), 4.84 (s, 2H), 7.04 (d, 1H), 7.25 (m, 5H), 7.43 (d, 1H), 8.06 (s, 1H), 8.69 (s, 1H), 13 (br s, 1H).

Sources & evidence

ORD record: ord-0f13176a66e94ad4a21a62cd5dd07801
Source dataset: uspto-grants-2011_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08022063B2

Reaction notes

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