2-(2-Chloro-4-fluorophenyl)acetamide → HCID 57658789, compound

HRID 910041Notes

Reaction equation

HRID 910041 reaction equation
C([O:3][C:4](=[O:18])[CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([Br:13])=[CH:9][C:8]=1[C:14](=O)[CH2:15]Br)C.[Cl:19][C:20]1[CH:25]=[C:24]([F:26])[CH:23]=[CH:22][C:21]=1[CH2:27][C:28]([NH2:30])=[O:29]>>[Br:13][C:10]1[CH:11]=[CH:12][C:7]([O:6][CH2:5][C:4]([OH:3])=[O:18])=[C:8]([C:14]2[N:30]=[C:28]([CH2:27][C:21]3[CH:22]=[CH:23][C:24]([F:26])=[CH:25][C:20]=3[Cl:19])[O:29][CH:15]=2)[CH:9]=1

Participants

3

Reactant 2

HCID 27737162-(2-Chloro-4-fluorophenyl)acetamideHCID 57658801[4-Bromo-2-(2-bromoacetyl)phenoxy]acetic acid ethyl ester

Product 1

HCID 57658789HCID 57658789, compound

Procedure

Title compound was prepared from [4-bromo-2-(2-bromoacetyl)phenoxy]acetic acid ethyl ester and 2-(2-chloro-4-fluorophenyl)acetamide according to GP5 and GP3: LC/MS (an 10p8) Rt 2.75 min, m/z 440 [M+H]+.

Sources & evidence

ORD record
ord-e008a07a7ea24c13b1b8d1c2b9df8eba
Source dataset
uspto-grants-2011_09
Patent number
US08022063B2

Reaction notes

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