HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetramethyltin → HCID 17985503, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetramethyltin | HCID 11661 | — |
| Reactant | 8-Bromo-6-methylimidazo[1,2-a]pyridine | HCID 15098896 | — |
| Catalyst | Tetrakis(triphenylphosphine)palladium | HCID 11979704 | — |
| Product | HCID 17985503 | HCID 17985503 | — |
Reaction Steps
Microwave a mixture of 6-methyl-8-bromoimidazo[1,2-a]pyridine (1.0 g, 4.76 mmol), tetramethyl tin (2.0 g, 11.2 mmol), and palladium tetrakis(triphenylphosphine) (0.28 g, 0.024 mmol) at 120° C. for 10 minutes at 300 watts. Subject the reaction mixture to flash silica gel chromatography to provide a quantitative yield of the title compound as a tan oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08022065B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-5942c99f32894f3e9acdad2d05e38f27 |
| Source note | uspto-grants-2011_09 |