HCID 67405279, compound → HCID 67404660, compound

Participants

Reaction Steps

Manganese dioxide (691 mg) was added to a solution of 1-[4-(6-iodoimidazo[1,2-a]pyridin-2-yl)phenyl]-1-ethanol (579 mg) in chloroform (50 mL), and the mixture was refluxed for 8 hours. The reaction mixture was filtered through Celite, and the mother liquor was concentrated. The residue was purified through silica gel column chromatography (dichloromethane:methanol=95:5), followed by concentration under reduced pressure, to thereby yield the title compound (371 mg).

Provenance & Evidence