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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 910223Generated: October 30, 2026

2-Amino-5-bromopyridine → 4-(6-Bromoimidazo[1,2-a]pyridin-2-yl)benzonitrile

https://huagongshe.com/reaction/910223

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-bromopyridineHCID 70622—
Reactant4-(Bromoacetyl)benzonitrileHCID 98654—
Product4-(6-Bromoimidazo[1,2-a]pyridin-2-yl)benzonitrileHCID 6740394383.5%

Reaction Steps

The procedure of Referential Example 1 was repeated, except that 2-amino-5-bromopyridine (692 mg) and 2-bromo-4′-cyanoacetophenone (450 mg) were used, to thereby yield the title compound (500 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08022075B2
Source datasetuspto-grants-2011_09
ORD IDord-17e6a4d25da34c6aa7a77afe04d0454b
Source noteuspto-grants-2011_09