Tosylmethyl isocyanide → HCID 25204120, compound

HRID 910224Notes

Reaction equation

HRID 910224 reaction equation
[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[N:6]([CH:8]=[C:9]([C:11]3[CH:18]=[CH:17][C:14]([CH:15]=[O:16])=[CH:13][CH:12]=3)[N:10]=2)[CH:7]=1.C1(C)C=CC(S([CH2:28][N+:29]#[C-:30])(=O)=O)=CC=1>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[N:6]([CH:8]=[C:9]([C:11]3[CH:18]=[CH:17][C:14]([C:15]4[O:16][CH:30]=[N:29][CH:28]=4)=[CH:13][CH:12]=3)[N:10]=2)[CH:7]=1

Participants

3

Reactant 2

HCID 161915Tosylmethyl isocyanideHCID 86631887HCID 86631887, compound

Product 1

HCID 25204120HCID 25204120, compoundYield 78.8%

Procedure

The procedure of Example 1 was repeated, except that 4-(6-bromoimidazo[1,2-a]pyridin-2-yl)benzaldehyde (255 mg) and p-toluenesulfonylmethylisocyanide (198 mg) were used, to thereby yield the title compound (227 mg).

Sources & evidence

ORD record
ord-a37423c4a4a04728aba48f0f9aaf03e4
Source dataset
uspto-grants-2011_09
Patent number
US08022075B2

Reaction notes

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