HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromophenyl isothiocyanate → 2-amino-4-bromobenzene-1-thiol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromophenyl isothiocyanate | HCID 16481 | — |
| Reactant | 1-(3-bromophenyl)thiourea | HCID 2735619 | — |
| Reactant | 5-Bromo-1,3-benzothiazol-2-amine | HCID 13775785 | — |
| Product | 2-amino-4-bromobenzene-1-thiol | HCID 12199294 | 21.1% |
Reaction Steps
The procedure of Referential Example 16 was repeated, except that 3-bromophenyl isothiocyanate (25.0 g) serving as a starting material was used, to thereby yield N-(3-bromophenyl)thiourea (19.4 g) as colorless crystals. Subsequently, The procedure of Referential Example 17 was repeated, to thereby yield 2-amino-5-bromobenzothiazole (1.21 g). Thereafter, The procedure of Referential Example 18 was repeated, to thereby yield the title compound (227 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08022075B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-ca815ff4795c42b7a281b92c22f6ffe2 |
| Source note | uspto-grants-2011_09 |