HCID 67390614, compound → HCID 24898949, compound

HRID 910256Notes

Reaction equation

HRID 910256 reaction equation
[CH2:1]([C:5]1[N:9]([C:10]2[N:15]=[C:14]([O:16][C:17]3C=CC=C[CH:18]=3)[C:13]([CH3:23])=[CH:12][N:11]=2)[N:8]=[CH:7][C:6]=1[C:24]([NH:26][CH2:27][C:28]1[N:32]([CH3:33])[CH:31]=[N:30][CH:29]=1)=[O:25])[CH2:2][CH2:3][CH3:4]>C(O)C>[CH2:1]([C:5]1[N:9]([C:10]2[N:15]=[C:14]([O:16][CH2:17][CH3:18])[C:13]([CH3:23])=[CH:12][N:11]=2)[N:8]=[CH:7][C:6]=1[C:24]([NH:26][CH2:27][C:28]1[N:32]([CH3:33])[CH:31]=[N:30][CH:29]=1)=[O:25])[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 1

HCID 67390614HCID 67390614, compound

Product 1

HCID 24898949HCID 24898949, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

Compound 16 was prepared following procedures described for compound 15 with the exception of substituting phenol with ethanol. 1H NMR (CDCl3) δ 0.88-0.91 (t, 3H), 1.35-1.39 (m, 2H), 1.44-1.47 (t, J=7.0 Hz, 3H), 1.60-1.63 (m, 2H), 2.20 (s, 3H), 3.49-3.52 (m, 2H), 3.66 (s, 3H), 4.48-4.52 (q, 2H), 4.64-4.65 (d, J=5.5 Hz, 2H), 7.02 (s, 1H), 7.47 (s, 1H), 7.83 (s, 1H), 8.33 (s, 1H). LCMS (ES+) m/z 398 (M+1).

Sources & evidence

ORD record
ord-60a22a2cdf3c4310804ba3da26c54514
Source dataset
uspto-grants-2011_09
Patent number
US08022061B2

Reaction notes

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