HCID 60207882, compound → HCID 67390680, compound

Participants

Reaction Steps

Compound 121 was prepared by similar procedure in Example 35 with the exception of substituting methyl 3-(aminomethyl)imidazo[1,2-a]pyridine-7-carboxylate and 5-butyl-1-[5-chloro-4-(cyclopropylamino)pyrimidin-2-yl]-1H-pyrazole-4-carboxylic acid. 1H NMR 400 MHz (CD3OD) δ: 8.63 (dd, J=7.43, 0.78 Hz, 1H), 8.26 (dd, J=1.56, 0.78 Hz, 1H), 8.23 (s, 1H), 7.97 (s, 1H), 7.79 (s, 1H), 7.51 (dd, J=7.43, 1.56 Hz, 1H), 4.95 (s, 2H), 3.96 (s, 3H), 3.63-3.57 (m, 2H), 2.95-2.88 (m, 1H), 1.61-1.51 (m, 2H), 1.32-1.22 (m, 2H), 0.91-0.78 (m, 5H), 0.73-0.66 (m, 2H). LCMS (ES+) m/z 523 (M+1).

Provenance & Evidence