Benzoyl chloride → HCID 67147870, compound

HRID 910287Notes

Reaction equation

HRID 910287 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([CH2:8][NH:9][CH3:10])[CH:5]=[N:6][CH:7]=1.[C:11](Cl)(=[O:18])[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[Br:1][C:2]1[CH:3]=[C:4]([CH2:8][N:9]([CH3:10])[C:11](=[O:18])[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH:5]=[N:6][CH:7]=1

Participants

3

Reactant 2

HCID 7412Benzoyl chlorideHCID 125150731-(5-Bromopyridin-3-yl)-N-methylmethanamine

Product 1

HCID 67147870HCID 67147870, compoundYield 90%

Procedure

In a manner similar to that of Example 2(f), starting with 0.5 g (3 mmol) of (5-bromopyrid-3-ylmethyl)methylamine and 0.4 ml (3.6 mmol) of benzoyl chloride, 0.8 g (90%) of N-(5-bromopyrid-3-ylmethyl) -N-methylbenzamide is obtained.

Sources & evidence

ORD record
ord-5cec06fb61594d9287754a4e6c8c15e3
Source dataset
uspto-grants-2011_09
Patent number
US08022079B2

Reaction notes

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