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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 91034Generated: October 25, 2026

Dichloromethane → 3-[6-(4-chloro-3-trifluoromethyl-phenoxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-propionic acid tert-butyl ester

https://huagongshe.com/reaction/91034

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
Reactanttert-Butyl acrylateHCID 15458—
ReactantDiisopropylethylamineHCID 81531—
Reactant6-(4-chloro-3-trifluoromethyl-phenoxymethyl)-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl esterHCID 69146288—
Product3-[6-(4-chloro-3-trifluoromethyl-phenoxymethyl)-3,4-dihydro-1H-isoquinolin-2-yl]-propionic acid tert-butyl esterHCID 69174089—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-aee23708678645cbad6569f7307cd1e7
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)