Water → 4-benzyl-5-isopropyl-3-(2,3,4,6-tetra-O-pivaloyl-betaD-glucopyranosyloxy)-1H-pyrazole

Participants

Reaction Steps

To a solution of 4-benzyl-1-ethoxycarbonyl-5-isopropyl-3-(2,3,4,6-tetra-O-pivaloyl-β-D-glucopyranosyl-oxy)-1H-pyrazole (0.15 g) in methanol (3 mL) was added sodium bicarbonate (0.032 g) under stirring at room temperature. The mixture was stirred at room temperature for 12 hours. In addition, to the mixture was added potassium carbonate (0.053 g), and the mixture was stirred for 2 hours. The reaction mixture was poured into water to precipitate the solid. The solids were collected by filtration. The obtained solids were washed with water and dried under reduced pressure to give 4-benzyl-5-isopropyl-3-(2,3,4,6-tetra-O-pivaloyl-β-D-glucopyranosyloxy)-1H-pyrazole (0.098 g).

Provenance & Evidence