alpha-Bromo-2-nitrotoluene → HCID 1252083, compound

HRID 910746Notes

Reaction equation

HRID 910746 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([O:11][CH2:12][CH3:13])[C:9]=1[OH:10])[CH:5]=[O:6].[N+:14]([C:17]1[CH:24]=[CH:23][CH:22]=[CH:21][C:18]=1[CH2:19]Br)([O-:16])=[O:15]>>[Br:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([O:11][CH2:12][CH3:13])[C:9]=1[O:10][CH2:19][C:18]1[CH:21]=[CH:22][CH:23]=[CH:24][C:17]=1[N+:14]([O-:16])=[O:15])[CH:5]=[O:6]

Participants

3

Reactant 2

HCID 77569alpha-Bromo-2-nitrotolueneHCID 6124963-Bromo-5-ethoxy-4-hydroxybenzaldehyde

Product 1

HCID 1252083HCID 1252083, compound

Procedure

Alkylation of 3-bromo-5-ethoxy-4-hydroxybenzaldehyde (5 g) with 2-nitrobenzylbromide (4.85 g) was performed according to the method described in example 1a. Yield: 7.88 g. MS-ESI: [M+H]+=380/382

Sources & evidence

ORD record
ord-07ee3de88b304224bebefc7e06c17bfd
Source dataset
uspto-grants-2011_09
Patent number
US08022218B2

Reaction notes

Loading…