Methyl 4-(bromomethyl)benzoate → HCID 86624410, compound

HRID 910749Notes

Reaction equation

HRID 910749 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([O:11][CH2:12][CH3:13])[C:9]=1[OH:10])[CH:5]=[O:6].[CH3:14][O:15][C:16](=[O:25])[C:17]1[CH:22]=[CH:21][C:20]([CH2:23]Br)=[CH:19][CH:18]=1>>[CH3:14][O:15][C:16](=[O:25])[C:17]1[CH:22]=[CH:21][C:20]([CH2:23][O:10][C:9]2[C:8]([O:11][CH2:12][CH3:13])=[CH:7][C:4]([CH:5]=[O:6])=[CH:3][C:2]=2[Br:1])=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 256687Methyl 4-(bromomethyl)benzoateHCID 6124963-Bromo-5-ethoxy-4-hydroxybenzaldehyde

Product 1

HCID 86624410HCID 86624410, compound

Procedure

Alkylation of 3-bromo-5-ethoxy-4-hydroxy benzaldehyde (4 g) with 4-bromomethylbenzoic acid methyl ester (3.73 g) was performed according to the method described in example 1a. Yield: 6.4 g. MS-ESI: [M+H]+=393/395

Sources & evidence

ORD record
ord-dbd482c8f9054fa3acc7f2edb494b19a
Source dataset
uspto-grants-2011_09
Patent number
US08022218B2

Reaction notes

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