HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl chloroformate → (2-Hydroxymethyl-phenyl)carbamic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl chloroformate | HCID 6586 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | HCID 5250324 | HCID 5250324 | — |
| Product | (2-Hydroxymethyl-phenyl)carbamic acid methyl ester | HCID 54236756 | — |
Reaction Steps
Reaction of aminobenzylalcohol (3 g) with methylchloroformate (1.9 ml) in the presence of DIPEA (12.8 ml) was performed according to the method described in example 22. The residue was chromatographed on silica gel in dichloromethane/ethyl acetate=25/1 as eluent. Yield: 4.19 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08022218B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-e86d56d26b9943a5a3ca7936ef4d82d8 |
| Source note | uspto-grants-2011_09 |