Pyridine → HCID 67390944, compound

Participants

Reaction Steps

The subtitle compound was prepared using the product from step i) (0.94 g) which was dissolved in pyridine (10 ml) and treated with acetyl chloride (0.22 ml) at 0 C. This was then allowed to warm to room temperature. The mixture was heated at reflux for 3 hours, diluted with 2M HCl, extracted with ethyl acetate, dried and concentrated under reduced pressure to an oil. The residue was purified by chromatography on silica eluting with diethyl ether/isohexane 3:1, yield 0.50 g.

Provenance & Evidence