2-Chloro-4-(ethylsulfonyl)-1-fluorobenzene → 4-Chloro-2-[2-chloro-4-(ethylsulfonyl)phenoxy]-benzenepropanoic acid

HRID 910858Notes

Reaction equation

HRID 910858 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][C:10]([OH:12])=[O:11])=[C:4]([OH:13])[CH:3]=1.[CH2:14]([S:16]([C:19]1[CH:24]=[CH:23][C:22](F)=[C:21]([Cl:26])[CH:20]=1)(=[O:18])=[O:17])[CH3:15]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][CH2:9][C:10]([OH:12])=[O:11])=[C:4]([O:13][C:22]2[CH:23]=[CH:24][C:19]([S:16]([CH2:14][CH3:15])(=[O:18])=[O:17])=[CH:20][C:21]=2[Cl:26])[CH:3]=1

Participants

3

Reactant 2

HCID 579047252-Chloro-4-(ethylsulfonyl)-1-fluorobenzeneHCID 673904453-(4-Chloro-2-hydroxyphenyl)propanoic acid

Product 1

HCID 116037814-Chloro-2-[2-chloro-4-(ethylsulfonyl)phenoxy]-benzenepropanoic acid

Procedure

The title compound was prepared by the method of example 3 step viii) using the product from step ii) and the product from example 4 step i).

Sources & evidence

ORD record
ord-a6aa0b488d7b40198626510570a2fe3d
Source dataset
uspto-grants-2011_09
Patent number
US08022248B2

Reaction notes

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