Benzene, 4-(ethylsulfonyl)-1-fluoro-2-(trifluoromethyl)- → 4-Chloro-2-[4-(ethylsulfonyl)-2-(trifluoromethyl)phenoxy]-benzenepropanoic acid

HRID 910866Notes

Reaction equation

HRID 910866 reaction equation
[CH2:1]([S:3]([C:6]1[CH:11]=[CH:10][C:9](F)=[C:8]([C:13]([F:16])([F:15])[F:14])[CH:7]=1)(=[O:5])=[O:4])[CH3:2].[Cl:17][C:18]1[CH:23]=[CH:22][C:21]([CH2:24][CH2:25][C:26]([OH:28])=[O:27])=[C:20]([OH:29])[CH:19]=1>>[Cl:17][C:18]1[CH:23]=[CH:22][C:21]([CH2:24][CH2:25][C:26]([OH:28])=[O:27])=[C:20]([O:29][C:9]2[CH:10]=[CH:11][C:6]([S:3]([CH2:1][CH3:2])(=[O:5])=[O:4])=[CH:7][C:8]=2[C:13]([F:16])([F:15])[F:14])[CH:19]=1

Participants

3

Reactant 2

HCID 66734206Benzene, 4-(ethylsulfonyl)-1-fluoro-2-(trifluoromethyl)-HCID 673904453-(4-Chloro-2-hydroxyphenyl)propanoic acid

Product 1

HCID 115682974-Chloro-2-[4-(ethylsulfonyl)-2-(trifluoromethyl)phenoxy]-benzenepropanoic acid

Procedure

The title compound was prepared by the method of example 3 step viii) using the product from step i) and the product from example 35 step ii).

Sources & evidence

ORD record
ord-31d4d5e381cc4cd294f7105acadde31c
Source dataset
uspto-grants-2011_09
Patent number
US08022248B2

Reaction notes

Loading…