Sodium hydride → HCID 63778831, compound

Participants

Reaction Steps

Using the method of Example 3, Step A, pyridine-2-thiol (0.526 g, 4.73 mmol), 60% sodium hydride in mineral oil (189 mg, 4.73 mmol), and 2-chloro-4-nitropyridine (0.750 g, 4.73 mmol) were reacted to provide 2-chloro-4-(pyridin-2-ylthio)pyridine (0.93 g, 88% yield) as a clear oil. 1H NMR (CDCl3) δ 8.61 (d, 1H), 8.25 (d, 1H), 7.71 (d, 1H), 7.44 (d, 1H), 7.31 (s, 1H), 7.25 (m, 1H), 7.19 (d, 1H).

Provenance & Evidence