HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-3-isothiocyanatopyridine → N-(4-(quinolin-5-yloxy)pyridin-2-yl)thiazolo[5,4-b]pyridin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-3-isothiocyanatopyridine | HCID 12868088 | — |
| Reactant | 4-(Quinolin-5-yloxy)pyridin-2-amine | HCID 66617947 | — |
| Product | N-(4-(quinolin-5-yloxy)pyridin-2-yl)thiazolo[5,4-b]pyridin-2-amine | HCID 57898978 | 3.83% |
Reaction Steps
The title compound was prepared according to the method of Example 180 from 4-(quinolin-5-yloxy)pyridin-2-amine and 2-chloro-3-isothiocyanatopyridine; (0.006 g, 3.83% yield) as a light yellow solid. 1H NMR (d6-DMSO) δ 11.47 (s, 1H), 9.00 (dd, 1H), 8.32 (m, 3H), 8.04 (d, 1H), 7.88 (t, 2H), 7.59 (dd, 1H), 7.51 (d, 1H), 7.38 (dd, 1H), 6.77 (dd, 1H), 6.66 (d, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08022222B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-6c59af746e43484bb3ccdcc83779270f |
| Source note | uspto-grants-2011_09 |