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HRID911528

反应详情

EQUATION

反应方程式

HRID 911528 的结构方程式

REACTANTS

反应物

2
结构：CC(=O)c1ccc(CBr)cc1
HCID583785

1-(4-(BROMOMETHYL)PHENYL)ETHANONE

C9H9BrO

结构：CN(C)C(=O)Sc1c(Cl)ccc2c1CCN(C(=O)OC(C)(C)C)CC2
HCID57655979

未命名化合物

PRODUCTS

生成物

1
结构：CC(=O)c1ccc(CSc2c(Cl)ccc3c2CCN(C(=O)OC(C)(C)C)CC3)cc1
HCID57656189

未命名化合物

PROCEDURE

实验过程

Use a method similar to the Example 380, using 3-tert-butoxycarbonyl-7-chloro-6-dimethylcarbamoylthio-2,3,4,5-tetrahydro-1H-benzo[d]azepine and 4-acetylbenzyl bromide to give, after chromatography eluting with hexane/EtOAc (15:1), the desired intermediate as a white solid. MS (APCI+) m/z 346 (M+H−Boc)+.

WORKUP

后处理

  1. customto give
  2. washafter chromatography eluting with hexane/EtOAc (15:1)