HCID 57656020, compound → HCID 57656545, compound

Participants

Reaction Steps

Dissolve 5-(3,3-dimethyl-but-1-ynyl)-2-cyano-pyridine (255 mg, 1.5 mmol) in methanol (15 mL). Add 10% Pd/C (Degussa type E101, 230 mg) and submit the mixture to hydrogenation under atmospheric pressure (balloon) overnight. Filter the catalyst through Celite® and concentrate the filtrate in vacuo to provide the title compound as a solid (231 mg, 87%) that was used without any further purification. MS (ES+) m/z: 193 (M+H)+.

Provenance & Evidence