HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[4-(Diethoxymethyl)phenyl]-3,3-dimethylbutan-1-ol → 1-[4-(Diethoxymethyl)-phenyl]-3,3-dimethylbutan-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[4-(Diethoxymethyl)phenyl]-3,3-dimethylbutan-1-ol | HCID 57656355 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Solvent | Hexane | HCID 8058 | — |
| Product | 1-[4-(Diethoxymethyl)-phenyl]-3,3-dimethylbutan-1-one | HCID 57656362 | 93% |
Reaction Steps
Dissolve 1-[4-(diethoxymethyl)-phenyl]-3,3-dimethylbutan-1-ol (3.8 g, 13.57 mmol) in hexane (50 mL). Add manganese dioxide (3.5 g, 40.71 mmol) and stir the mixture at 60° C. overnight. Filter the solid and concentrate the filtrate in vacuo to give the desired intermediate as a colorless oil (3.49 g, 93%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08022062B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-937eb670761b4d08a9adbc9a7ac430b5 |
| Source note | uspto-grants-2011_09 |