HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromo-7-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-6-nitrofuro[3,2-c]pyridine → 3-Bromo-7-[(R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]furo[3,2-c]pyridin-6-ylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromo-7-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-6-nitrofuro[3,2-c]pyridine | HCID 57812350 | — |
| Catalyst | Hydrochloric acid-iron | HCID 86633186 | — |
| Product | 3-Bromo-7-[(R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]furo[3,2-c]pyridin-6-ylamine | HCID 57812725 | — |
Reaction Steps
3-Bromo-7-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-6-nitrofuro[3,2-c]pyridine (Intermediate 9a) was reacted with iron/HCl as described in Example 2 to give 3-Bromo-7-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]furo[3,2-c]pyridin-6-ylamine (=racemic Example 2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08022206B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-d2089770822b4bf9bd2dd1a710d054bd |
| Source note | uspto-grants-2011_09 |