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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 912078Generated: November 3, 2026

3-Pyridinemethanamine → 4-(3-Methoxy-phenyl)-2-morpholin-4-yl-7-pyridin-3-ylmethyl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidine

https://huagongshe.com/reaction/912078

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-PyridinemethanamineHCID 31018—
Reactant4-[4-Chloro-5-(2-chloroethyl)-6-(3-methoxyphenyl)-pyrimidin-2-yl]morpholineHCID 59244988—
Product4-(3-Methoxy-phenyl)-2-morpholin-4-yl-7-pyridin-3-ylmethyl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidineHCID 59244818—

Reaction Steps

In the same manner as Example 1-A-01, from 4-[4-chloro-5-(2-chloroethyl)-6-(3-methoxyphenyl)-pyrimidin-2-yl]-morpholine and 3-aminomethylpyridine, the desired compound was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08022205B2
Source datasetuspto-grants-2011_09
ORD IDord-61e25751dae14f8887fab3c7fd9c6726
Source noteuspto-grants-2011_09