1H-Indazol-5-amine → HCID 59244223, compound

HRID 912079Notes

Reaction equation

HRID 912079 reaction equation
Cl[C:2]1[C:7]([CH2:8][CH2:9]Cl)=[C:6]([C:11]2[CH:16]=[CH:15][CH:14]=[C:13]([O:17][CH3:18])[CH:12]=2)[N:5]=[C:4]([N:19]2[CH2:24][CH2:23][O:22][CH2:21][CH2:20]2)[N:3]=1.[NH:25]1[C:33]2[C:28](=[CH:29][C:30]([NH2:34])=[CH:31][CH:32]=2)[CH:27]=[N:26]1>>[NH:25]1[C:33]2[C:28](=[CH:29][C:30]([N:34]3[C:2]4[N:3]=[C:4]([N:19]5[CH2:24][CH2:23][O:22][CH2:21][CH2:20]5)[N:5]=[C:6]([C:11]5[CH:16]=[CH:15][CH:14]=[C:13]([O:17][CH3:18])[CH:12]=5)[C:7]=4[CH2:8][CH2:9]3)=[CH:31][CH:32]=2)[CH:27]=[N:26]1

Participants

3

Reactant 2

HCID 880121H-Indazol-5-amineHCID 592449884-[4-Chloro-5-(2-chloroethyl)-6-(3-methoxyphenyl)-pyrimidin-2-yl]morpholine

Product 1

HCID 59244223HCID 59244223, compound

Procedure

In the same manner as Example 1-A-01, from 4-[4-chloro-5-(2-chloroethyl)-6-(3-methoxyphenyl)-pyrimidin-2-yl]-morpholine and 1H-indazol-5-ylamine, the desired compound was obtained.

Sources & evidence

ORD record
ord-dc04d93835be4fa783c1b4ea10beb3c5
Source dataset
uspto-grants-2011_09
Patent number
US08022205B2

Reaction notes

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