HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 43501540, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 3-Amino-1-propanol | HCID 9086 | — |
| Reactant | m-Bromobenzenesulphonyl chloride | HCID 17943 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 43501540 | HCID 43501540 | — |
Reaction Steps
3-Bromo-N-(3-hydroxy-propyl)-benzenesulfonamide (266 mg) obtained from the reaction of pyridine, 3-aminopropanol and 3-bromobenzenesulfonyl chloride in acetonitrile was left to act in di-tert-butyl carbonate (226 mg) and acetonitrile (5 ml) in the presence of DMAP (10 mg), to obtain 3-bromo-N-Boc-N-(3-hydroxy-propyl)-benzenesulfonamide as a colorless oil (267 mg, 72%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08022205B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-f237dca8fb644aa7b113ee0be3ce897a |
| Source note | uspto-grants-2011_09 |