4-Bromo-3-methylbenzoic acid → HCID 67385396, compound

Participants

Reaction Steps

Using bis-(4-methoxy-benzyl)-[5-(2-morpholin-4-yl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-pyrimidin-2-yl]-amine (100 mg) and 4-bromo-3-methylbenzoic acid (60 mg) instead of 4-bromobenzoic acid, in the same manner as Step A in Example 1-D-19, a crude product of 4-(4-{2-[bis-(4-methoxy-benzyl)-amino]-pyrimidin-5-yl}-2-morpholin-4-yl-5,6-dihydro-pyrrolo[2,3-d]pyrimidin-7-yl)-3-methyl-benzoic acid (31 mg, 25%) was obtained.

Provenance & Evidence