HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexanone → HCID 17906154, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexanone | HCID 7967 | — |
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Sulfuric Acid | HCID 1118 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 17906154 | HCID 17906154 | 51.9% |
Reaction Steps
A 100 mL flask was charged with 3.02 g of cyclohexanone, 3.19 g of 1-methylpiperazine, 25 mL of ethanol, 3 drops of concentrated sulfuric acid and a catalytic amount of Pd/C, typically 5 mol %. A balloon filled with hydrogen gas was attached. After stirring for 4 days the reaction mixture was filtered through Celite and concentrated to give 2.91 g of 1-methyl-4-cyclohexylpiperazine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08025863B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-18c601eddfd84527a8fa1942031d6c12 |
| Source note | uspto-grants-2011_09 |