HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-tert-Butyloxycarbonylamino-2-piperidone → HCID 57736559, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-tert-Butyloxycarbonylamino-2-piperidone | HCID 124787 | — |
| Reactant | (2-Bromoethoxy)-tert-butyldimethylsilane | HCID 3608067 | — |
| Product | HCID 57736559 | HCID 57736559 | — |
Reaction Steps
(S)-tert-butyl 1-(2-(tert-butyldimethylsilyloxy)ethyl)-2-oxopiperidin-3-ylcarbamate was prepared from (S)-tert-butyl 2-oxopiperidin-3-ylcarbamate (Example 7) and (2-bromoethoxy)(tert-butyl)dimethylsilane according to the general procedure of Example 9. The crude product was purified by column chromatography, eluting with 50% ethyl acetate/hexanes, to provide compound (2d) in 26% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026233B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-78a723c5e827433faa7dee67c80bfa69 |
| Source note | uspto-grants-2011_09 |